更新日付:2025年1月23日

高齢者機能評価+老年医学的介入

(Geriatric Assessment and management (GAM)またはGeriatric Assessment-Driven Intervention (GAIN))

高齢者機能評価の結果をその先のマネージメントに活かしていくこと。複数のランダム化比較試験でその有用性が検証されている1)-5)。

  1. Warren MW. Care of the chronic aged sick. Lancet. 1946;1(6406):841-3.
  2. Mohile SG, Mohamed MR, Xu H, et al. Evaluation of geriatric assessment and management on the toxic effects of cancer treatment (GAP70+): a cluster-randomised study. Lancet. 2021;398(10314):1894-904.
  3. Mohile SG, Epstein RM, Hurria A, et al. Communication With Older Patients With Cancer Using Geriatric Assessment: A Cluster-Randomized Clinical Trial From the National Cancer Institute Community Oncology Research Program. JAMA Oncol. 2020;6(2):196-204.
  4. Soo WK, King MT, Pope A, et al. Integrated Geriatric Assessment and Treatment Effectiveness (INTEGERATE) in older people with cancer starting systemic anticancer treatment in Australia: a multicentre, open-label, randomised controlled trial. Lancet Healthy Longev. 2022;3(9):e617-e27.
  5. Li D, Sun CL, Kim H, et al. Geriatric Assessment-Driven Intervention (GAIN) on Chemotherapy-Related Toxic Effects in Older Adults With Cancer: A Randomized Clinical Trial. JAMA Oncol. 2021;7(11):e214158